Margo Harshman’s portrayal of Alex Jensen, Sheldon’s diligent and ambitious assistant, added a new dynamic to The Big Bang Theory. Alex’s romantic interest in Leonard created tension between her and Penny, adding an extra layer of complexity to the show.
Following her time on The Big Bang Theory, Margo continued to make her mark in the television industry, securing a recurring role on the popular series NCIS. In her personal life, Margo had a romantic relationship with fellow actor Chris Marquette in the early 2000s. Chris is known for his roles in movies such as The Girl Next Door and Fanboys.
Wil Wheaton and Anne Wheaton
Will Wheaton's portrayal of himself on The Big Bang Theory began with a rocky start, as he initially clashed with Sheldon and his friends. However, as the series progressed, their relationship evolved into a close friendship. In the real world, Will rose to fame with his role in the beloved film Stand By Me, directed by Rob Reiner, and even had a spell on Star Trek.
His real-life partner, Anne Prince, is also an actress, having appeared in notable works such as Sharknado and Tabletop. Together, they form a talented duo, sharing a passion for the entertainment industry and supporting each other in their respective careers.
Laurie Metcalf and Matt Roth
Laurie Metcalf's portrayal of Sheldon's devout and overbearing Christian mother, Mary Cooper, garnered recognition and praise from audiences. However, she is perhaps best known for her iconic role as Jackie Harris in the beloved sitcom Roseanne. In a twist of fate, Laurie found love with her Roseanne co-star, Matt Roth, who played her character's abusive on-screen boyfriend.
Their on-set romance spilled over into real life, and they tied the knot in 1993. Tragically, their relationship didn't stand the test of time, and they divorced in 2014. Despite the end of their marriage, they remain dedicated parents to their three children—a daughter and two sons—who continue to be a source of joy and pride in their lives.
Josh Brener and Meghan Falcone
Josh Brener's portrayal of the comic book store employee on The Big Bang Theory added a touch of geeky humor to the show. His character often interacted with the main cast, providing comedic moments and showcasing his knowledge of all things nerdy. Outside of The Big Bang Theory, Josh gained significant recognition for his role as Nelson "Big Head" Bighetti in the HBO series Silicon Valley.
His portrayal of the quirky tech genius solidified his comedic talent and made him a fan favorite. In 2014, Josh tied the knot with actress Meghan Falcone, whom he met while performing together at the Upright Citizens Brigade Theatre. Meghan has also made her mark in the entertainment industry, having acted in shows such as Californication and Foursome.
John Ross Bowie and Jamie Denbo
John Ross Bowie's portrayal of the eccentric and less likable Dr. Kripke on The Big Bang Theory showcased his comedic talent. The character's distinctive speech impediment, unable to pronounce the letters R or L, added a unique twist to his performance. In reality, John has displayed his versatility as an actor, having appeared in shows like Reno 911! and The Citizens' Brigade.
His range extends beyond his on-screen roles, as he is married to the talented actress and comedian Jamie Denbo. Jamie is known for her role in Ghostbusters and her work as a comedian. Their dynamic as a couple highlights the stark contrast between John's character's speech issues and their shared passion for comedy and entertainment.